Engineering proximal vs. distal heme–NO coordination via dinitrosyl dynamics: implications for NO sensor design
نویسندگان
چکیده
منابع مشابه
Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design.
Proximal vs. distal heme-NO coordination is a novel strategy for selective gas response in heme-based NO-sensors. In the case of Alcaligenes xylosoxidans cytochrome c' (AXCP), formation of a transient distal 6cNO complex is followed by scission of the trans Fe-His bond and conversion to a proximal 5cNO product via a putative dinitrosyl species. Here we show that replacement of the AXCP distal L...
متن کاملEngineering proximal vs. distal heme–NO coordination via dinitrosyl dynamics: implications for NO sensor design† †Electronic supplementary information (ESI) available: Structure factors and atomic coordinates have been deposited in the RCSB Protein Data Bank with accession codes; 5JT4, 5JLI, 5JP7, 5JRA, 5JVE, 5JUA, 5JSL, 5JS5. See DOI: 10.1039/c6sc04190f Click here for additional data file.
School of Biological Sciences, University of CO4 3SQ, UK. E-mail: [email protected] Department of Chemistry and Biochemistry Oregon 97850, USA. E-mail: candrew@eou. Faculty of Science and Education Science, Iraq Medical Research Center, Hawler Medical Swiss Light Source, Paul Scherrer Institute, Manchester Institute of Biotechnology, 131 School of Chemistry, Bangor University, Ba Molecular Bio...
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ژورنال
عنوان ژورنال: Chemical Science
سال: 2017
ISSN: 2041-6520,2041-6539
DOI: 10.1039/c6sc04190f